Advanced Testing

Medical Diagnostic Testing Clinic Woburn

In order to get to the root of the problem rather than just treating symptoms, it is necessary for the doctor to take a thorough history, perform a physical exam, and confirm the diagnosis with appropriate testing. While we use standard blood and urine testing, as do most physicians, we also have access to some of the most advanced diagnostic tests and procedures. Some of the tests we offer are:

Body Composition Testing using the BioSpace 520, the machine used for Olympic athletes and professional sports teams. This device accurately determines pounds of fat, muscle, and water and where they are located. It is essential for monitoring weight loss and the results of a proper diet or exercise program.

Salivary hormone testing by ZRT labs and Genova Diagnostics. Salivary hormone testing is the most accurate noninvasive method of evaluating adrenal function and is very useful in monitoring testosterone, estradiol, estriol, estrone, progesterone, and DHEA as well as melatonin. It does not require a blood draw, so it can be done at home. It is the standard of care in research on stress and adrenal function.

Urinary hormone analysis by  Genova diagnostics. Urine testing is very useful for monitoring hormone levels including thyroid, growth hormone, and aldosterone as well as testosterone, estrogens, progesterone, cortisol, dhea, and their metabolites. In addition, with urine testing we can assess the activity of osteoporosis and whether the patient's hormones are being converted into safe or dangerous compounds. If a problem is detected, we can then intervene. For women with a family history of breast and ovarian cancer or men with a family history of prostate cancer, this test is essential. Often, there is a familial tendency for cetain liver enzymes to process estrogens incorrectly resulting in toxic, cancer-causing metabolites. Urine hormone analysis and the estronex test can detect this condition and steps can be taken to repair this abnormality. These patients will benefit from a nutritional supplement program that targets these defective enzyme systems, moving them toward normal function, and hopefully reducing the risk for hormonally related cancer.

Lyme Disease and Tick-Borne Disease Testing. The blood tests typically ordered by your family doctor to diagnose Lyme Disease are very inaccurate; only about half of the patients who actually have Lyme bacteria growing in their bodies will have a positive result by these commonly ordered tests(IFA or Western Blot). For this reason, the diagnosis of Lyme Disease is a clinical one (based on symptoms and history) and should not be ruled out simply because an insensitive blood test is negative. Because the common Lyme tests are so unhelpful, we use the Igenex Laboratory for testing due to their much higher accuracy in detecting the Lyme pathogen and other parasites that accompany it. 

The Nutreval, by Genova Diagnostics - the most advanced multiphasic nutritional diagnostic panels available, evaluating vitamins, fatty acids, minerals, toxic metals, mitochondrial function, yeast overgrowth, intestinal dysbiosis, detoxification, oxidative stress, neurotransmitter synthesis, urine and serum amino acid levels, coenzymeQ10, and vitamin D levels. About 150 separate tests are done on a fasting urine/blood sample obtained in our office. This is the ultimate in customizing a nutritional program for a patient.

Spectracell Nutritional Testing uses your own living white blood cells to determine if you have any nutritional deficiencies.

Food Sensitivity Testing - evaluating up to 154 different foods and food ingredients.

Complete Diagnostic Stool Analysis by Genova, This test is done using polymerase chain reaction testing (PCR), and state of the art proteomics, the most sensitive method of detecting parasites and disease causing bacteria. In addition, it monitors inflammation, digestion, levels of digestive enzymes, and absorption of nutrients.

The Heidelberg Gastric pH Monitoring System, www.phcapsule.com. Dr. Kaye is one of the few doctors nationally to have invested in this cutting edge system to determine whether you are making enough stomach acid to properly digest your food. Many people have symptoms of acid reflux, but often the cause is low stomach acid-not too much. Lack of stomach acid can result in deficiencies of B12, vitamin D, Iron, Calcium and the inability to digest protein, leading to food allergies and deficiencies of neurotransmitters. In addition, the undigested food rots in the colon leading to gas, bloating, and "irritable bowel." This condition, once diagnosed, is treatable with great improvement of these symptoms.

Hydrogen and Methane Breath Testing to detect SIBO (Small Intestine Bacterial Overgrowth); a cause of bloating and diarrhea and irritable bowel.

Sphygmocore Central Arterial Blood Pressure Monitoring System, www.atcormedical.com. The Sphygmocore was developed at Johns Hopkins University and is the most advanced system available to noninvasively measure the elasticity of your arteries, the work output of your heart, the central blood pressure (blood pressure at your heart), and accurately determine the "age" of your arteries. You are only as old as your arteries, since they carry nutrients and oxygen to all the organs of your body. It is critically important to know if your arteries are aging faster than your years or, hopefully, are more youthful than your years. If you are prematurely ageing, we can intervene to reverse this process.

Toxicity testing to determine if you are contaminated by environmental pesticides such as DDT, carcinogens, industrial and chemical pollutants, or heavy metals. If so, we can prescribe effective methods of removing these harmful substances from your body.

Genetic testing through Genova Diagnostics to evaluate genetic mutations in various systems including detoxification, osteoporosis, cardiovascular health, immune function. If you understand what your genetic risks are, you can take steps to minimize their harmful effects.

Telomere Length Testing by Life Length. Telomere testing allows us to accurately determine your biological age by measuring the length of the telomeres at the end of each chromosome. If they are excessively short, i.e., excessively aged, we can intervene to reverse this process using the revolutionary new compound TA-65 developed by Geron Pharmaceuticals.

Mycotoxin Urine Testing by Real Time Labs.  Urine mycotoxins are produced by toxic molds/fungi that could be living in your body or you are exposed to them in your environment.  They can cause chronic fatigue, chronic rhino-sinusitis, cognitive difficulties, a fibro-myalgia syndrome and irritable bowel syndrome.  The first step to getting better is to detect these mycotoxins and then, if present, we can advise you on the next steps to take to get better.

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Joseph Edward Kaye, MD

300 Trade Center, Suite 4400, Woburn, MA 01801
Phone: 781-933-4200 · Fax: 781-933-1553
Monday - Friday 8:00am - 4:30pm